Sobre Chlamydia pneumoniae

Chlamydophila pneumoniae is a species of Chlamydophila, an obligate intracellular bacterium that infects humans and is a major cause of pneumonia. It was known as the Taiwan acute respiratory agent (TWAR) from the names of the two original isolates – Taiwan (TW-183) and an acute respiratory isolate designated AR-39. Until recently, it was known as Chlamydia pneumoniae, and that name is used as an alternate in some sources. In some cases, to avoid confusion, both names are given. This atypical bacterium commonly causes pharyngitis, bronchitis, coronary artery disease and atypical pneumonia in addition to several other possible diseases including atherosclerosis. Also, the bacteria would play an important role in the exacerbation of asthma. It is found in nearly 60 % of asthmatic children between the ages of 5 and 15 years, and there is a direct link between the importance of the immune response against Chlamydia and the frequency of seizures.

Pruebas disponibles para Chlamydia pneumoniae

EliSpot

Chlamydia pneumoniae EliSpot
(2x tubo ACD/CPDA)

IFT, ELISA, Immunoblot

Anticuerpos Chlamydia pneumoniae-IgA y Chlamydia pneumoniae-IgG
(1x Tubo de suero/SST)

PCR

Chlamydia pneumoniae-PCR en sangre
(2x tubo EDTA o esputo, secreción faríngea)

Bacteria:

Chlamydophila pneumoniae (gram-negativa, intracelular)

Vectores / Transmisión:

Transmitida por el aire, de humano a humano, garrapatas (no ha sido probado; reactivada en la enfermedad de Lyme)

Huéspedes:

los caballos, los koalas y las ranas están infectados

Síntomas:

Tos, ligero dolor de garganta, voz ronca, sinusitis, neumonía atípica, meningoencefalitis, bronquiolitis obliterante, miocarditis, Síndrome de Guillain-Barré

tras la infección (4-6 semanas):

artritis (reactiva, no diferenciada), tendovaginitis

Se asocia con:

Ej. Enfermedad de Alzheimer, Esclerosis Múltiple, Depresiones, Fibromialgia, Síndrome de Fatiga Crónica (SFC), ataques de corazón, Accidente Cerebrovascular Agudo (AIS), arterioesclerosis, Autismo, Parkinson, Artritis Reumatoide, Asma

Factores de riesgo:

inmunosupresión (niños, mayores)