Chlamydia pneumoniae

Chlamydophila pneumoniae is a species of Chlamydophila, an obligate intracellular bacterium that infects humans and is a major cause of pneumonia. It was known as the Taiwan acute respiratory agent (TWAR) from the names of the two original isolates – Taiwan (TW-183) and an acute respiratory isolate designated AR-39. Until recently, it was known as Chlamydia pneumoniae, and that name is used as an alternate in some sources. In some cases, to avoid confusion, both names are given. This atypical bacterium commonly causes pharyngitis, bronchitis, coronary artery disease and atypical pneumonia in addition to several other possible diseases including atherosclerosis. Also, the bacteria would play an important role in the exacerbation of asthma. It is found in nearly 60 % of asthmatic children between the ages of 5 and 15 years, and there is a direct link between the importance of the immune response against Chlamydia and the frequency of seizures.

Test disponibili per Chlamydia pneumoniae

EliSpot

Elispot per Chlamydia pneumoniae
(2x provetta ACD/CPDA)

IFT, ELISA, Immunoblot

Anticorpi Chlamydia pneumoniae-IgA e Chlamydia pneumoniae-IgG
(1x provetta da siero/SST)

PCR

Chlamydia pneumoniae-PCR nel sangue
(2x provette EDTA o espettorato, secrezione faringea)

Batteri:

Chlamydophila pneumoniae (gram-negativo, intracellulare)

Vettore / Trasmissione:

infezioni aeree, trasmissione tra esseri umani, zecche (non provato; probabile riattivazione nella malattia di Lyme)

Ospiti:

cavalli, koala e rane possono essere infettati

Ospiti:

tosse, leggero dolore alla gola, raucedine, sinusite, polmonite atipica, meningoencefalite, bronchiolite obliterante, miocardite, sindrome di Guillain-Barré

dopo l'infezione (4-6 settimane):

artrite (reattiva, indifferenziata), tendovaginite

Associazioni:

es. morbo di Alzheimer, sclerosi multipla, depressioni, fibromialgia, sindrome da fatica cronica (CFS), attacchi di cuore, ictus ischemico acuto (AIS), arteriosclerosi, autismo, Parkinson, artrite reumatoide, asma

Fattori di rischio:

immunosoppressione (bambini/persone anziane)