Foire aux questions

La version 12.0 est actuellement valide.

Veuillez noter que nous avions besoin de mettre à jour certains de nos prix d'essai à partir du 1er avril 2019. Si vous avez des kits de test plus anciens, veuillez nous contacter. Nous vous enverrons alors la nouvelle liste de prix.
Tous les kits de test reçus dans notre laboratoire après le 1er juin 2019 qui contiennent des versions plus anciennes (11.1,11.0,10.0,...), doivent être facturés avec les nouveaux prix.
Merci de votre compréhension.

ArminLabs has developed checklists for Lyme and co-infections to offer a free preanalytic tool for patients and health specialists/physicians. These checklists help to decide which tests are necessary. This enables users to increase the outcome and reduce costs.
In the event of a complicated medical history the patient or his health professional are invited to discuss with us whether it is advisable to add further tests relating to immunology, rheumatology and co-infections.
ArminLabs does not run any in-house tests of its own design, and is in constant exchange with the test producers on improving test performance and reducing any test limitations.

“We have to be very careful in not overinterpreting such experimental test systems like the so-called “LymeSpot revised”. We do not think it is really a fact that Interleukin 2 will tell us the answer for patients by an easy red-green light-system until there is some data about specificity and sensitivity for the standard use of Interleukin 2.”
(Statement of German Professor for Experimental Science)
ArminLabs is not offering the “LymeSpot revised” test because there is no validation or any study for the "revised" LymeSpot. For several experts it is an experimental test without actual data and validation behind it.
Also, the specialists at ArminLabs, are not sure whether using just Interleukin 2 can really give a definite answer for "yes" or "no" for treatment (easily called by laboratories offering “LymeSpot revised” and interpreting as "red-green light traffic principle"). ArminLabs has received information from several scientific experts for cytokines that Interleukin 1, Interleukin 4, Interleukin 6, Interleukin 10 and especially Interleukin 8 also play a very important role in the activity of infections in general. So just for scientific purposes the "revised" LymeSpot test might give among all other mentioned cytokines an additional information, but not in routine laboratory use. It might be also very dangerous in correct treatments for patients to say:" Green symbol = treatment and Red symbol and Red/Green = Don’t know what to do or no treatment". Laboratory medicine is not that easy.
Therefore ArminLabs has decided to wait for the validation and the first study (which has been running for several years now according the test producers) of “LymeSpot revised”.
ArminLabs will continue to use the established Elispot like all other big laboratories in Germany and Europe. The diagnostic approach of ArminLabs is not to change to an experimental test system until we have full clarity about the correct cytokine profiles in Lyme disease and other infections.
“[…] I totally agree. IL-2 is not a good parameter by itself. I am working on a paper with Elispot + versus - and cytokines.”
(Statement of Belgium Professor for physiology)

The producer of all EliSpot tests did a study with around 400 samples to figure out whether the additional VlsE and p41i are good parameters for interferon gamma release assay. VlsE is a good marker for serological tests, but it turned out that there is almost no response in interferon gamma testing. p41i is also a good serological marker, but it’s not a specific marker. p41i is also contained in the lysate of the Borrelia burgdorferi Full antigen. There is no scientific evidence for the higher accuracy of the so-called “Elispot 2” compared to the Elispot. In our opinion the higher price is not justified and does not provide any benefit to the patient.
Manufacturer’s statement:
"[…] 409 patients suspected for or with reported tick bite(s) in the past were tested for reactive T-cells after stimulation with Borrelia antigens […]
For the evaluation, positive donors in different disease stages were tested with individual proteins / peptides for published or known epitopes. The amount of T-cells which secrete IFNg after stimulation with VlsE and Bmp is low or practically non-existent. […] Although the Borrelia proteins VlsE, Bmp and p41 are well established and show a good concordance with the clinical picture in serological tests like ELISA or Western Blot, their potential to activate specific T-cells in the EliSpot is relatively low. Based on our studies and collaborations with external diagnostic laboratories, the overall results show that beside the Borrelia lysate the native OspC and the recombinant DbpA used are the most efficient activators for Borrelia specific T-cells."

ArminLabs is certified by the German Accreditation Board DAkks, international accreditation no. DIN EN ISO 15189:2014. Our accreditation certificate
An overview of the offered tests can be found in our Schedule of Services.
We do not carry out any in-house tests of our own design. Every test we perform is commercially available, certified and validated internally by ArminLabs and externally by the test producers. For every test a positive and a negative control is always being performed to check for influencing factors.

   

Heures de bureau

  • Lundi - Jeudi:
    08:00 - 12:00 ; 12:30 - 16:30
  • Vendredi:
    08:00 - 12:00 ; 12:30 - 15:30
  • Samedi - Dimanche:
    Fermé
  • Horaire Allemagne: Samedi, 11:27