“We have to be very careful in not overinterpreting such experimental test systems like the so-called “LymeSpot revised”. We do not think it is really a fact that Interleukin 2 will tell us the answer for patients by an easy red-green light-system until there is some data about specificity and sensitivity for the standard use of Interleukin 2.”
(Statement of German Professor for Experimental Science)
ArminLabs is not offering the “LymeSpot revised” test because there is no validation or any study for the "revised" LymeSpot. For several experts it is an experimental test without actual data and validation behind it.
Also, the specialists at ArminLabs, are not sure whether using just Interleukin 2 can really give a definite answer for "yes" or "no" for treatment (easily called by laboratories offering “LymeSpot revised” and interpreting as "red-green light traffic principle"). ArminLabs has received information from several scientific experts for cytokines that Interleukin 1, Interleukin 4, Interleukin 6, Interleukin 10 and especially Interleukin 8 also play a very important role in the activity of infections in general. So just for scientific purposes the "revised" LymeSpot test might give among all other mentioned cytokines an additional information, but not in routine laboratory use. It might be also very dangerous in correct treatments for patients to say:" Green symbol = treatment and Red symbol and Red/Green = Don’t know what to do or no treatment". Laboratory medicine is not that easy.
Therefore ArminLabs has decided to wait for the validation and the first study (which has been running for several years now according the test producers) of “LymeSpot revised”.
ArminLabs will continue to use the established Elispot like all other big laboratories in Germany and Europe. The diagnostic approach of ArminLabs is not to change to an experimental test system until we have full clarity about the correct cytokine profiles in Lyme disease and other infections.
“[…] I totally agree. IL-2 is not a good parameter by itself. I am working on a paper with Elispot + versus - and cytokines.”
(Statement of Belgium Professor for physiology)